Protein Creatinine Ratio Formula:
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The Protein Creatinine Ratio (PCR) is a laboratory test that measures the amount of protein in urine relative to the amount of creatinine. It provides a standardized assessment of proteinuria and is used to screen for and monitor kidney disease.
The calculator uses the Protein Creatinine Ratio formula:
Where:
Explanation: The ratio standardizes protein excretion to creatinine excretion, correcting for variations in urine concentration.
Details: PCR is crucial for detecting and monitoring proteinuria, which is a key marker of kidney damage. It helps in diagnosing various kidney disorders and assessing treatment effectiveness.
Tips: Enter urine protein and urine creatinine values in mg/dL. Both values must be greater than zero for accurate calculation.
Q1: What are normal PCR values?
A: Normal PCR is typically less than 150 mg/g. Values between 150-500 mg/g indicate microalbuminuria, while values above 500 mg/g suggest macroalbuminuria.
Q2: Why use PCR instead of 24-hour urine collection?
A: PCR provides a quick and convenient alternative to 24-hour urine collection, with good correlation and easier patient compliance.
Q3: When should PCR be measured?
A: PCR should be measured when screening for kidney disease, monitoring patients with diabetes or hypertension, and assessing response to treatment.
Q4: Are there limitations to PCR?
A: PCR may be less accurate in patients with very low or very high muscle mass, as creatinine excretion correlates with muscle mass.
Q5: How often should PCR be checked?
A: Frequency depends on the underlying condition, but typically annually for high-risk patients and more frequently if abnormal results are found.