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Protein Creatinine Ratio Formula:
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The Protein Creatinine Ratio (PCR) is a clinical measurement used to quantify proteinuria in urine samples. It provides a more accurate assessment of protein excretion than random urine protein measurements alone, as it corrects for urine concentration.
The calculator uses the Protein Creatinine Ratio formula:
Where:
Explanation: The formula converts the ratio to standardized mg/g units for clinical interpretation and comparison.
Details: PCR is crucial for screening and monitoring proteinuria in various kidney diseases, diabetes, hypertension, and other conditions affecting renal function. It helps in early detection of kidney damage and monitoring treatment response.
Tips: Enter urine protein in mg/dL and urine creatinine in g/L. Both values must be positive numbers. First morning void urine samples are preferred for most accurate results.
Q1: What is a normal PCR value?
A: Normal PCR is typically less than 150 mg/g. Values between 150-500 mg/g indicate microalbuminuria, while values above 500 mg/g suggest macroalbuminuria.
Q2: Why use PCR instead of 24-hour urine collection?
A: PCR provides a reliable estimate of protein excretion without the inconvenience and potential errors of 24-hour urine collection.
Q3: When should PCR be measured?
A: PCR should be measured in patients with diabetes, hypertension, family history of kidney disease, or those showing signs of renal impairment.
Q4: Are there limitations to PCR measurement?
A: PCR may be less accurate in patients with very low or very high muscle mass, as creatinine excretion varies with muscle mass.
Q5: How often should PCR be monitored?
A: Frequency depends on the underlying condition, but typically annually for diabetic patients and more frequently if abnormal values are detected.