1. What is Protein to Creatinine Ratio?

The Protein to Creatinine Ratio (PCR) is a diagnostic test that measures the amount of protein in urine relative to creatinine. It's used to detect and monitor proteinuria, which can indicate kidney damage or disease.

2. How Does the Calculator Work?

The calculator uses the PCR formula:

Where:

• Urinary Protein — Protein concentration in urine (mg/dL)
• Urinary Creatinine — Creatinine concentration in urine (mg/dL)
• 1000 — Conversion factor to express result in mg/g

Explanation: The ratio normalizes protein excretion to creatinine excretion, providing a more accurate assessment than random urine protein measurements alone.

3. Importance of PCR Calculation

Details: PCR is a reliable method for quantifying proteinuria and is used to screen for kidney disease, monitor treatment response, and assess prognosis in various renal conditions.

4. Using the Calculator

Tips: Enter both urinary protein and urinary creatinine values in mg/dL. Both values must be positive numbers to calculate a valid ratio.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal PCR value?
A: Normal PCR is typically less than 150 mg/g. Values between 150-500 mg/g indicate microalbuminuria, and values above 500 mg/g indicate macroalbuminuria.

Q2: Why use PCR instead of 24-hour urine collection?
A: PCR provides a reliable estimate of protein excretion without the inconvenience and potential errors of 24-hour urine collection.

Q3: When should PCR be measured?
A: PCR is typically measured in first morning urine samples for the most accurate results, though random samples can also be used.

Q4: Are there limitations to PCR?
A: PCR may be less accurate in individuals with very high or very low muscle mass, as creatinine excretion correlates with muscle mass.

Q5: How often should PCR be monitored?
A: Frequency depends on the underlying condition, but typically every 3-6 months for patients with known kidney disease or diabetes.