1. What is Protein Creatinine Ratio?

The Protein Creatinine Ratio (PCR) is a diagnostic test used to quantify protein excretion in urine. It provides a more accurate assessment of proteinuria than a simple dipstick test and helps monitor kidney function.

2. How Does the Calculator Work?

The calculator uses the PCR formula:

Where:

• \( Protein \) — Protein concentration in urine (mg/L)
• \( Creatinine \) — Creatinine concentration in urine (mmol/L)

Explanation: The ratio normalizes protein excretion to creatinine excretion, accounting for variations in urine concentration.

3. Importance of PCR Calculation

Details: PCR is crucial for detecting and monitoring proteinuria, which is a key indicator of kidney damage. It helps diagnose and manage various kidney diseases, including diabetic nephropathy and glomerulonephritis.

4. Using the Calculator

Tips: Enter protein concentration in mg/L and creatinine concentration in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal PCR value?
A: Normal PCR is typically less than 15 mg/mmol. Values between 15-50 mg/mmol indicate microalbuminuria, and values above 50 mg/mmol indicate macroalbuminuria.

Q2: Why use PCR instead of 24-hour urine collection?
A: PCR provides a reliable estimate of protein excretion without the inconvenience and potential errors of 24-hour urine collection.

Q3: When should PCR be measured?
A: PCR should be measured when screening for kidney disease in high-risk patients (e.g., diabetics, hypertensives) and for monitoring known kidney disease.

Q4: Are there limitations to PCR?
A: PCR may be less accurate in individuals with very high or very low muscle mass, as creatinine excretion depends on muscle mass.

Q5: How often should PCR be checked?
A: Frequency depends on the underlying condition. Diabetics should be screened annually, while patients with known kidney disease may need more frequent monitoring.